use tetrabutyl ammonium phospate in stead of tetrabutyl ammonium sulphate

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mohd
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use tetrabutyl ammonium phospate in stead of tetrabutyl ammonium sulphate

dear sir
hi
can u tell what will  happens to my rs (releated substances) if i will use tetrabutyl ammonium phospate in stead of  tetrabutyl ammonium sulphate in my m.phase

Dr. Analytical
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If your rs compounds have a

If your rs compounds have a negative charge, then they will form ion pairs with the tetrabutyl ammonium part of the molecule.  The phosphate does not participate in the ion pairing.  However, it will affect the pH of the mobile phase, but sulphate will not.  If your compounds are not senstive to pH, then there may be no difference.