uv metod for valdecoxib

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humaira
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uv metod for valdecoxib

sir/madam,

please help me regarding the solubility of valdecoxib in oils.

vanishing
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this might help:
vanishing
vanishing's picture
Cited from:

Cited from:
Liu et al., 2004
J. Chem. Eng. Data 2004, 49, 1847

Valdecoxib is chemically designated as 4-(5-
methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide and is a
diaryl substituted isoxazole (see Figure 1). It has poor
solubility in water, that is, 10 íg/mL at 298.15 K.

The structure looks pretty unpolar and there is good solubility in 100%EtOH (>10 mg/ml)
So I suppose solubility in oil is high.

But what is your question? Do you want actual numbers?

p.s.:
if you use GOOGLE (!) and enter "solubility" and "valdecoxib", you get quite a few hits......