Greetings from the Analytical Chemistry forum!
I need a little (OK, maybe a lot) general information on monoclonal antibodies. Being a chemist with only some biochemistry in my background, I have been asked to assist with an analysis of a monoclonal antibody product. I believe one of the questions relates to aggregation, and the lab will be using a chromatographic technique to assess this (that's where I come in). At this time I do not have any specifics on the material; that will come later.
What I need now is a little help getting started. Is there a primer or general introduction to this field that I can get somewhere? I would like information on how these things are made, their structure, and behavior in solution. I realize there are thousands (millions?) of possible materials, so at this point I would like to get a sense on what the field is about in its most general terms, and get an idea on the range of antibodies that are out there. From there, I will be able to see where this particular one fits into the grander scheme.
Thanks in advance!