Antibodies

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StephenJones1
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Antibodies

Hello,

I have only idea that Antibodies are produced by a type of white blood cell called a plasma cell. Antibodies can occur in two physical forms, a soluble form that is secreted from the cell, and a membrane-bound form that is attached to the surface of a B cell and is referred to as the B cell receptor (BCR). Some antibodies act by binding to certain essential enzymes in the target bacteria. So, I want to know that how might these antibiotics influence the chemical reactions controlled by the enzymes and what is the anticipated effect on the bacteria? Any idea regarding my doubts, please share with me.

Thanks
Stephen Jones

g a
g a's picture
 Hi

 Hi

ANtibodies have specific antigen determining regions .....epitopes that are corresponding to agreotope.
Antibodies have a variable and constant region and in that constant region is a domain called Fc. Fc region binds to its corresponding receptors on the cells like Macrophages etc (Opsonization) which then trigger various actios including phagocytosis.

In case an Ab is bound to an enzyme, It may alter catalytic activity by inducing conformational change in enzyme structure or by altering its active site or still completely rendering it inactive if Ab binds to the active site and masks it completely from substrate.

scienceyou
scienceyou's picture
Antibodies and antibiotocs

Antibodies and antibiotocs are two different concepts.

Antibodies are what your body produces in response to the presence of antigens (bacterial or viral surface structures). They merely assist your white blood cells in identifying and destroying invading microorganisms. Antibiotics are chemicals that work to destroy invading bacteria, usually by disrupting the outer cell wall and making it "leak" or by messing up the bacteria's metabolic processes.