coenzymes

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Kutty
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coenzymes

why coenzymes are non derivative of fat soluble vitamins?

Sami Tuomivaara
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Kutty,

Kutty,

I think there are two main reasons, First, as fat soluble vitamins (and their derivatives) are not soluble in water, the delivery of these vitamins to the soluble proteins (that need those coenzymes) poses a problem... Also, fat soluble vitamins don't generally have a lot of reactive functional groups (hydroxyls, carboxylic acids...) which are needed for participation in various  reactions... If coenzyme has this kind of functional groups, it would be most likely water soluble. I'd be interested in hearing expert's answers on this because it is an interesting question...

Cheers,

scchaudhary
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Hi  KuttyI

Hi  KuttyI
In my opinion Coenzymes are oil i.e fat soluble vitamin which has hydrocarbon portion which is hydrophobic in nature. It is because of the absence of  reactive sites like HYDROXYL, AMINO, CARBOXY group in coenzyme it can not form H- bonding with water molecule . These grps are essential for reactions.Therefore these vitamin cannot react with  soluble protein  .For example 1,4 benzoquinonewhich is a coenzyme  has no such funtional reactive group.Therefore , coenzymes may be non-derivative of fat soluble vitamine
Chaudhary SC
 

Kutty
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Thank u for information ur

Thank u for information ur idea very useful to me

Kutty
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Thank u sir

Thank u sir