PhD. Student: Regulation of Gene Transcription by RNA polymerase II and its Role in Development of Human Disease (Ovarian Cancer)
A PhD. position is available at the Central European Institute of Technology (CEITEC), Brno, Czech Republic, in the group of Dalibor Blazek (lab pages at: http://www2.ceitec.muni.cz/blazek-lab/ ). The project focuses on transcription cycle-related cyclin-dependent kinases (mainly Cdk9 and Cdk12) involved in the regulation of gene transcription by RNA Polymerase II and their roles in modulation of DNA damage responses (see our recent papers: Blazek et al., Genes and Development. 2011; Blazek, Cell Cycle, 2012; Ekumi et al, Nucleic Acids Research, 2015 in press).
The successful candidate will join a team of young motivated people dedicated to understand mechanisms of control of gene expression by RNA Polymerase II. Our final goal is to understand how deregulation of the gene expression mechanisms lead to the onset of cancer; particularly the role of Cdk12 in the onset of ovarian cancer is of our main interest. Our projects are currently funded by CEITEC and grants from the Czech Academy of Sciences.
CEITEC (http://www.ceitec.eu) is a newly established European research center of scientific excellence and its laboratories offer state-of-the-art equipment at the new campus of Masaryk University. Information for foreign researchers about the Czech Republic can be found at: http://www.msmt.cz/file/18138
The candidate must be highly motivated, self-driven with an excellent academic record and hold a Master´s degree (or be close to its completion) in molecular biology, biochemistry or in a related field of life sciences. Applicant must have a strong interest in molecular biology; interest in bioinformatics and cancer biology is a big plus. Good communication and interpersonal skills and fluency in spoken and written English are required. Expected start date is immediately or upon agreement. Contract type: 12 months, with possibility for extension depending on performance. The position is not associated with any teaching obligations.
Please send application (including CV, short statement of research background/ interests and the contact information of at least two references) by email to Dr. Dalibor Blazek at firstname.lastname@example.org.