Cancer and immunosuppression

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canscientist's picture
Cancer and immunosuppression

Do any cancer cause immunosuppression?

mahi's picture
Please find the attached and

Please find the attached and click the following link

g a
g a's picture
cancers doesnt cause

cancers doesnt cause immunosuppression , however the tumor cells ivade the immune surveillance and escape the elimination by immune system.

Omai's picture
Actually, tumors can directly

Actually, tumors can directly contribute to immunosuppression. They can release galectin-1 which induces apoptosis in activated TH1 cells.
Here is a reference
And this just scratches the surface. Tumors use multiple mechanisms to evade the immune system.
Here is a review from Nature that details these studies.
This is a very interesting and emerging field. I think we are just learning how sophisticated the interaction is between tumors and the immune system.

ghassan's picture
cancer does not cause

cancer does not cause immunosuppression but treating cancer with chemmicals can cause immunosuppression
while escape of cancer cells from immune response may contibuted to tolerance