anti-cancer mechanism

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kranthi
kranthi's picture
anti-cancer mechanism

Hi,
can anybody tell me the simple procedure to find out the DNA binding activity of anticancer drugs

Arvind Singh Pundir
Arvind Singh Pundir's picture
Hi Kranthi,

Hi Kranthi,

please go through the following review from Current Opinion in Biotechnology, hope it adds in solving your querry
"DNA as a target for anticancer compounds: methods to determine the mode of binding and the mechanism of action"
www.scs.uiuc.edu/~phgroup/pdfs/ref50_CurrOpinBiotechnol_Palchaudhuri_PDFReprint.pdf