induction and inhibition of apoptosis

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Susan Murphy
Susan Murphy's picture
induction and inhibition of apoptosis

I am trying to design an experiment in which I want to both induce and inhibit apoptosis.  I have read that I can induce apoptosis using actinomycin D or camptothesin.
What can I use to treat cells to inhibit apoptosis preferably in a non-specific manner as I am not at this point trying to find a target.?

Thanks for your help

Sue

Raashmi
Raashmi's picture
Dear Murphy,

Dear Murphy,

If you are going to use Camptothecin as Apoptosis inducer then there are many inhibitors available.
Kindly go through the article it may give you some idea.

http://www.gotofcm.com/pdf/2003710181702hl60apop.pdf