I think the pro-apoptotic stimulus and cell type that you would be using would be an important factor in your decision. For example, if you were looking at the apoptosis inducing ability of certain bacteria which were commonly found in one organ, then you may wish to first use an in vitro culture of that cell type, and then subsequently model that infection in vivo.
I think the pro-apoptotic stimulus and cell type that you would be using would be an important factor in your decision. For example, if you were looking at the apoptosis inducing ability of certain bacteria which were commonly found in one organ, then you may wish to first use an in vitro culture of that cell type, and then subsequently model that infection in vivo.