end-repair of PCR products

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lina11301's picture
end-repair of PCR products


We plan to utilize baits in our research, albeit not sonicated fragments of DNA but rather PCR products.
As such, we wanted to inquire whether end-repair of our baits, before biotinylated adapter-ligation, is necessary, given the fact that PCR products are already blunt-ended themselves?
Thank you for your help in this matter.