end-repair of PCR products

1 post / 0 new
lina11301
lina11301's picture
end-repair of PCR products

 

We plan to utilize baits in our research, albeit not sonicated fragments of DNA but rather PCR products.
 
As such, we wanted to inquire whether end-repair of our baits, before biotinylated adapter-ligation, is necessary, given the fact that PCR products are already blunt-ended themselves?
 
Thank you for your help in this matter.