Firemaster 550 contains AHR agonist with AHR-independent cardiotoxicity

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Jon Moulton
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Firemaster 550 contains AHR agonist with AHR-independent cardiotoxicity

Gerlach CV, Das SR, Volz DC, Bisson WH, Kolluri SK, Tanguay RL. Mono-substituted isopropylated triaryl phosphate, a major component of Firemaster 550, is an AHR agonist that exhibits AHR-independent cardiotoxicity in zebrafish. Aquat Toxicol. 2014 May 16;154C:71-79. doi: 10.1016/j.aquatox.2014.05.007. [Epub ahead of print]