siRNA and alternative splicing

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Jon Moulton
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siRNA and alternative splicing

More targets for siRNA:

Control of alternative splicing through siRNA-mediated transcriptional gene silencing.

Alló M, Buggiano V, Fededa JP, Petrillo E, Schor I, de la Mata M, Agirre E, Plass M, Eyras E, Elela SA, Klinck R, Chabot B, Kornblihtt AR.

Nat Struct Mol Biol. 2009 Jun 21. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/19543290
This describes a new application for siRNA; it also describes more mechanisms behind the off-target gene modulation associated with siRNAs.  For more along that topic, see my blog [23 Jun 2009 | Tuesday]  .