Trapping Mutants via Expression-Based Insertional Mutagenesis Screening

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Jon Moulton
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Trapping Mutants via Expression-Based Insertional Mutagenesis Screening

Ding Y, Liu W, Deng Y, Jomok B, Yang J, Huang W, Clark KJ, Zhong TP, Lin X, Ekker SC, Xu X.  Trapping Cardiac Recessive Mutants via Expression-Based Insertional Mutagenesis Screening.  Circ Res. 2013 Feb 15;112(4):606-17. doi: 10.1161/CIRCRESAHA.112.300603. Epub 2013 Jan 2.

Phenotypes of mutations induced by transposon-based genetraps were reverted to wild-type by early injection of Morpholino to transposon's engineered splice-switch target .