What are the causes and consequences of Genomic Instability connected to DNA repair pathways.
That is a huge question!
In fact, there is an entire Keystone conference devoted to this topic alone. Here is the webpage (which contains abstracts and talk titles that may help you begin your search into this exciting field of research).http://www.keystonesymposia.org/Meetings/viewMeetings.cfm?MeetingID=979
DNA repair comes in many forms. Here is a link to a review on base excision repair (BER) and its role in genomic stability. I hope this begins to answer your question.