You will find plenty of information on the ENCODE project here. Essentially, ENCODE is a project aimed at doing very detailed annotation/characterization of a representative subset of the human genomic sequence.
The project aims to analyze functional elements of DNA including in the 5'/promoter, introns and 3' region of gene/message.
http://www.genome.gov/10005107
'The National Human Genome Research Institute (NHGRI) launched a public research consortium named ENCODE, the Encyclopedia Of DNA Elements, in September 2003, to carry out a project to identify all functional elements in the human genome sequence. The project started with two components - a pilot phase and a technology development phase.
The pilot phase tested and compared existing methods to rigorously analyze a defined portion of the human genome sequence (See: ENCODE Pilot Project). The conclusions from this pilot project were published in June 2007 in Nature and Genome Research [genome.org]. The findings highlighted the success of the project to identify and characterize functional elements in the human genome. The technology development phase also has been a success with the promotion of several new technologies to generate high throughput data on functional elements.'
The pilot project analyzed 1% of human genome.
NHGRI is also innvolved in other projects: modENCODE: DNA element analysis in model organisms ( fruit fly D. melanogaster, roundworm C. elegans) The Knockout Mouse Project a comprehensive and public resource comprised of mice containing a null mutation in every gene in the mouse genome Cancer Genome Atlas full-scale effort to systematically explore the entire spectrum of genomic changes involved in human cancer using genome analysis technologies
You will find plenty of information on the ENCODE project here. Essentially, ENCODE is a project aimed at doing very detailed annotation/characterization of a representative subset of the human genomic sequence.
The project aims to analyze functional elements of DNA including in the 5'/promoter, introns and 3' region of gene/message.
http://www.genome.gov/10005107
'The National Human Genome Research Institute (NHGRI) launched a public research consortium named ENCODE, the Encyclopedia Of DNA Elements, in September 2003, to carry out a project to identify all functional elements in the human genome sequence. The project started with two components - a pilot phase and a technology development phase.
The pilot phase tested and compared existing methods to rigorously analyze a defined portion of the human genome sequence (See: ENCODE Pilot Project). The conclusions from this pilot project were published in June 2007 in Nature and Genome Research [genome.org]. The findings highlighted the success of the project to identify and characterize functional elements in the human genome. The technology development phase also has been a success with the promotion of several new technologies to generate high throughput data on functional elements.'
The pilot project analyzed 1% of human genome.
NHGRI is also innvolved in other projects:
modENCODE: DNA element analysis in model organisms ( fruit fly D. melanogaster, roundworm C. elegans)
The Knockout Mouse Project a comprehensive and public resource comprised of mice containing a null mutation in every gene in the mouse genome
Cancer Genome Atlas full-scale effort to systematically explore the entire spectrum of genomic changes involved in human cancer using genome analysis technologies
Ryan u r really informative.
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Varsha, u gave a insight of addition works. thanks a lot..