Cyclic peptides

3 posts / 0 new
Last post
wwierda
wwierda's picture
Cyclic peptides

Is anyone familiar with cyclic peptides that block intetrin binding and function as antigonists to cell-cell or cell-matrix interactions?

jbreaux
jbreaux's picture
I'm not familiar with

I'm not familiar with intetrins. Are they cell-cell/cell-matrix adhesion molecules related to integrins?

mo
mo's picture
wwierda wrote:Is anyone

wwierda wrote:

Is anyone familiar with cyclic peptides that block intetrin binding and function as antigonists to cell-cell or cell-matrix interactions?

If you mean integrin, cyclic peptides have been tried for some time. They are better than linear peptide, but not as good as Antibodies. Hard to synthesize as well.