IL-2 involved in Th1 cell response. IL-2 is also necessary during T cell development in the thymus for the maturation of a unique subset of T cells that are termed regulatory T cells.
A recombinant form of IL-2 for clinical use is manufactured by Chiron Corporation with the brand name Proleukin. It has been approved by the Food and Drug Administration (FDA) for the treatment of cancers (malignant melanoma, renal cell cancer), and is in clinical trials for the treatment of chronic viral infections, and as a booster (adjuvant) for vaccines.
wrote:
This sounds like an undergrad essay question. Why not Wiki?
http://en.wikipedia.org/wiki/Interleukin_2
Interleukin-2 is a highly immunogenic cytokine. But the use as medicine is still continued.
IL-2 involved in Th1 cell response. IL-2 is also necessary during T cell development in the thymus for the maturation of a unique subset of T cells that are termed regulatory T cells.
A recombinant form of IL-2 for clinical use is manufactured by Chiron Corporation with the brand name Proleukin. It has been approved by the Food and Drug Administration (FDA) for the treatment of cancers (malignant melanoma, renal cell cancer), and is in clinical trials for the treatment of chronic viral infections, and as a booster (adjuvant) for vaccines.
Here is the useful link..
http://en.wikipedia.org/wiki/Interleukin-2
A couple of nice reviews:
http://www3.interscience.wiley.com/journal/121495433/abstract?CRETRY=1&SRETRY=0
http://www.medscimonit.com/fulltxt.php?ICID=869403