interleukin in allegy

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canscientist's picture
interleukin in allegy


Fraser Moss
Fraser Moss's picture
That is too broad a question.

That is too broad a question.

Which allergy in particular are you interested in? It will vary depending on the type of allergy.

If you have access you should look at this article

Allergy Asthma Proc. 2007 Jan-Feb;28(1):10-5

New insights into the pathophysiology of allergic rhinitis.
Rosenwasser L.

Department of Medicine, and Basic Science, University of Missouri-Kansas City School of Medicine 64108, USA. eval(unescape('%64%6f%63%75%6d%65%6e%74%2e%77%72%69%74%65%28%27%3c%61%20%68%72%65%66%3d%22%6d%61%69%6c%74%6f%3a%6c%72%6f%73%65%6e%77%61%73%73%65%72%40%63%6d%68%2e%65%64%75%22%3e%6c%72%6f%73%65%6e%77%61%73%73%65%72%40%63%6d%68%2e%65%64%75%3c%2f%61%3e%27%29%3b'))

The immune response to an allergen is dependent on an initial sensitization process, with future exposures triggering a two-part allergic response including an early and a late phase. The process by which an allergen is recognized as such, including which cell types and cytokines are involved in the sensitization process, has become clearer over the last several years. Similarly, the roles of the different preformed mediators responsible for many of the signs and symptoms of the early phase response have been elucidated. Recent work also has shed some light on the multitude of cells and mediators involved in the late-phase reactions, which can lead to priming and long-term inflammation. This article will discuss some of this recent work as well as review the basics behind all of the stages of the allergic response, especially as they apply to the nose and upper airway.

PMID: 17390750 [PubMed - indexed for MEDLINE]