Gene variant linked to robust flu vaccine response

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Prabakaran Mani...
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Gene variant linked to robust flu vaccine response

              Variant forms of a gene might tip off doctors to people who are naturally more or less likely to benefit from a flu vaccination. A new study of the gene variants’ effect also suggests a novel approach to boosting immunity, researchers say, that could be particularly helpful in elderly or immune-compromised people who generate subpar responses to vaccines.
Variations in the interleukin-28B gene, which encodes an immune system signaling protein, might account for some of the differences in protection seen among people getting the flu shot. Some harbor a form of the gene that induces a cell to produce less of the signaling protein.