Transplantation problems between Twins

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Backialakshmi D...
Backialakshmi Dharmalingam's picture
Transplantation problems between Twins

I read that If transplantation is done between identical twins problems are less as the genetic variation is less between them... My question is The mitochondrial DNA is inherited separately from the mother and it is different for each and every person and it codes for its own protiens .. What will be the impact of mitochondrial protiens when transplantation is done between identical twins? Wont it produce any rejection action against the foriegn organ ? Does it consider that organ as its own?
                                                                                             Please clarify.... expecting the answer...
                                                                                             Backia Lakshmi Dharmalingam

Satinder
Satinder's picture
Dear Backia Lakshmi

Dear Backia Lakshmi Dharmalingam
Inheritance of the maternal mitochondrion genes in the child are linked to a special trait called as maternal inheritance. However the mitochondrion genes are derived from the same line as twins will have same mother and in case of identical twins the Single ZYgote divides after the fertilization before the cleavage divisions start. Hence the identical twins will have the same set of derived maternal genes as well as chromosomal inheritence too.

Backialakshmi D...
Backialakshmi Dharmalingam's picture
Thank u for the reply ..

Thank u for the reply .. Thanks for the immediate reply and clarifying my doubt.. Thak u sir Mr. SATINDER