Biological Chemistry and Drug Discovery (BCDD) (http://www.lifesci.dundee.ac.uk/research/bcdd) is a multidisciplinary Division within the College of Life Sciences at the University of Dundee. According to The Research Excellence Framework 2014 (REF 2014) Dundee is rated the top University in the UK for Biological Sciences. The division, which occupies modern laboratories with state of the art facilities, includes both research in fundamental biology and translational research as exemplified by the Drug Discovery Unit (www.drugdiscovery.dundee.ac.uk). A key area of research for BCDD is the kinetoplastids, organisms which cause a variety of diseases in humans and animals.
We are seeking to appoint a highly motivated researcher with appropriate skills in organic chemistry and chemical biology to join a newly formed research team investigating mechanisms of action of potential novel drugs in trypanosomatid parasites. The team will work alongside existing research groups within BCDD, employing cutting edge tools for target identification and mode of action studies in Trypanosoma brucei, Leishmania spp. and T. cruzi. The role of this post will be to design and synthesize probe and tool molecules for genomic and proteomic studies by biologists in the mode of action team and to provide chemical support to the Fairlamb group (http://www.lifesci.dundee.ac.uk/people/alan-fairlamb), who work in related areas of kinetoplastid biology.
A Ph.D. in organic chemistry is essential
Experience in organic synthesis is essential
Experience in chemical proteomics is desirable
Experience in chemical biology is desirable
Computer and data processing/management skills
Ability to work independently and/or as part of a team
Good communication skills – written/verbal
Track record of publication in peer-reviewed journals
A few facts about The College of Life Sciences at Dundee:
The College of Life Sciences has over 900 research and support staff from 59 countries and external funding in excess of £40 million per year
Dundee has twice been named ‘the best place to work in Europe’ in a poll of scientists conducted by The Scientist magazine
The College of Life Sciences in the University of Dundee has been rated the top University in the UK for Biological Sciences in the 2014 Research Excellence Framework
Dundee, set on the east coast of Scotland, lies in an area of outstanding natural beauty, including large sandy beaches and challenging hills.