Head of Laboratory - Nutritional Biochemistry

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Head of Laboratory - Nutritional Biochemistry

MRC Human Nutrition Research HNR Unit

Salary From - £35,935 per annum

MRC Human Nutrition Research (HNR) is a specialist Unit from within the Medical Research Council that is dedicated to nutrition research aimed at improving human health. HNR also acts as an independent, authoritative source of scientific advice and information on nutrition and health in order to foster evidence-based nutrition policy and practice.
As a result of department development, we wish to appoint a Head for our Nutritional Biochemistry Laboratory (NBL). The NBL is a suite of specialist laboratories at HNR, which provide modern analytical facilities across the scope of HNR's research activities. The NBL sits within the Nutritional BioAnalysis (NBA) Group providing key central analytical provision, in which vitamins, certain minerals, and a wide range of clinical chemistry indices are assayed. The aim of the NBL is to provide efficient and effective throughput of sample analyses, to develop new analysis as required and to be responsive to HNR's overall research direction and mission. 
The laboratory is looking to expand its repertoire of assays for the measurement of vitamins, their metabolites and other nutritionally relevant biochemicals through the use of mass spectrometry and requires senior expertise in quantitative mass spectrometry to develop and oversee this aspect of the laboratory's portfolio, in addition to providing high level strategic development and support for the laboratory.
The post-holder will be responsible for demonstrating leadership and proactivity in the pursuit of involvement with projects and surveys requiring analytical involvement and for the scientific and technical aspects of the entire lab. He/she is expected to work closely and positively with all members of NBA, and wider staff and visitors to the Unit, to produce an integrated approach to the work of the NBL both internally across HNR and with external collaborators. He/she is required to work with the Director, Department Heads, Group Leaders and delegated senior members of staff, to ensure the analytical work is delivered, new assays established and the standing of NBA and HNR are maintained.
The intent is to introduce quantitative mass spectrometry based on mass spec and chromatography equipment (e.g. LC-tandem MS) as an analytical platform in NBA. The post-holder will be required to lead the development and implementation of analysis of vitamin status markers based on quantitative mass spectrometry, initially focusing on folate and vitamin D.  To achieve this, the post-holder will need expert working knowledge of quantitative mass spectrometry and assay development. He/she will have primary responsibility for the instrumentation allocated to this work, interacting closely with the biological mass spectrometry team in the Lipidomics Laboratory and scientists throughout HNR requiring such analysis or expert oversight of quantitative mass spectrometric analyses, most particularly those researching vitamin D metabolism in the Director's Programme.
This is a full time role with salary dependant on qualifications and experience. In addition to your salary we offer an extensive benefits package including over 30 days annual leave, free on site car parking and optional membership of MRC's final salary pension scheme.
For an informal discussion about the post please contact Dr Ann Prentice on 01223 426356.

Applications are handled by the RCUK Shared Services Centre; to apply please visit our job board at https://ext.ssc.rcuk.ac.uk and complete an online application form.  Applicants who would like to receive this advert in an alternative format (e.g. large print, Braille, audio or hard copy), or who are unable to apply online should contact us by telephone on 01793 867003, Please quote reference number IRC16108. 

Closing date: 31st March 2011
Interview date: w/c 11th April 2011

Final appointments will be subject to a pre employment screening
The Medical Research Council is an Equal Opportunities Employer
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