biofilm removal

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wee p
wee p's picture
biofilm removal

Can anyone tell me if passivation of a stainless steel tank will remove or inactivate a biofilm?

Arvind Singh Pundir
Arvind Singh Pundir's picture
passivation process of

passivation process of cleaning stainless steel tanks involves cleaning with NaOH and citric acid followed by nitric acid (up to 20% at 120F) and a complete water rinse. This process will restore the film, remove metal particles, dirt, and welding generated compounds (e.g. oxides).

In the context of corrosion, passivation is the spontaneous formation of a hard non-reactive surface film that inhibits further corrosion. This layer is usually an oxide or nitride that is a few atoms thick
if both the above process are followed Biofilm can be removed
Interesting article to go through
BIOFILM FORMATION AND CONTROL IN FOOD PROCESSING FACILITIES members.ift.org/NR/rdonlyres/1F685508-6646-4F2E-9D3F-9FC132D0E949/0/crfsfsv02n1p022032ms20010630.pdf
also referHow to remove Biofilm in water system  www.askaboutvalidation.com/forum/showthread.php

Shubhangi
Shubhangi's picture
It is  acid and alkali

It is  acid and alkali treatment and it should remove biofilm.
does anyone want to note pharmacopoeial take on this? Is it part of cleaning validation?

vvaldez
vvaldez's picture
Hi wee p, go to www.astropak

Hi wee p, go to www.astropak.com.  Astro Pak is the passivation expert in the U.S.  They even have a blog where you can ask their Chief Scientist all of your cleaning and passivation questions.  It's called "As Doc".  Good luck!

Shubhangi
Shubhangi's picture
Hi visit this site. they have

Hi visit this site. they have good experience
http://www.orbitindustries.com/pages/pickle%20and%20passivate/pass.htm