I have been formulating nanoparticles by Ionic gelation method taking Capecitabine as the drug and chitosan as the polymer and I'm also using TPP as a crosslinking agent.
I need to find out the entrapment efficiency and drug loading of my nanospheres but first of all I need to understand
- what is the difference between the two and
-what is the methodology of finding out these two?
please help me!!