ENTRAPMENT EFFICIENCY and DRUG LOADING

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Arati
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ENTRAPMENT EFFICIENCY and DRUG LOADING

 I have been formulating nanoparticles by Ionic gelation method taking Capecitabine as the drug and chitosan as the polymer and I'm also using TPP as a crosslinking agent.

I need to find out the entrapment efficiency and drug loading of my nanospheres but first of all I need to understand
- what is the difference between the two and
-what is the methodology of finding out these two?

please help me!!