Mouse Spinal Injections

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aab1091
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Mouse Spinal Injections

Hi,

I need to inject a solution to the mouse's brain. however, I need to do so on adult brains and with a large molecule. I think a spinal injection is the only way I think I can do so. Any thought?

Guest (not verified)
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Wrong!.

Wrong!.
Look up the methods for IVC. intraventricular injections. 

aab1091
aab1091's picture
Thanks, but do you have any

Thanks, but do you have any articles or websites to get me started with this?

Guest (not verified)
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It really is a very simple

It really is a very simple proceedure.  Takes about 20 min.

Abnormal olfactory function demonstrated by manganese-enhanced MRI in mice with experimental neuropsychiatric lupus.
Kivity S, Tsarfaty G, Agmon-Levin N, Blank M, Manor D, Konen E, Chapman J, Reichlin M, Wasson C, Shoenfeld Y, Kushnir T.
Ann N Y Acad Sci. 2010 Apr;1193(1):70-7.

J Alzheimers Dis. 2010;19(2):691-704.
Insulin-resistant brain state after intracerebroventricular streptozotocin injection exacerbates Alzheimer-like changes in Tg2576 AbetaPP-overexpressing mice.
Plaschke K, Kopitz J, Siegelin M, Schliebs R, Salkovic-Petrisic M, Riederer P, Hoyer S.