Help in choice of cell lines for drug analysis

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Avene
Avene's picture
Help in choice of cell lines for drug analysis

I am currently given a project to check on the cytotoxicity of a drug on 2 cell lines ( a liver cancer cell line and a breast cancer cell line) and then do a comparison of protein expression in the 2 cell lines that were affected by the drug.

What puzzled me is how could I compare two cell lines when the 2 of them are totally different cell lines? I tried asking this question to everyone in the lab, including the professor who assigned me the project but I could not get an answer.

Hope someone here can help me. Thank you very much.