Parkinson's disease

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Dominiquest
Dominiquest's picture
Parkinson's disease

Can anyone please tell me the exact process taking place in the development of Parkinson's disease? I heard from sources that the dopamine producing cells are connected only to the region in the fore brain where they transfer dopamine in order to signal movement and stopping of movement.... My question is, do the dopamine producing cells have connections to any other part of the brain or the body, and if so, where exactly?   I would much appreciate a detailed explaination...
Thank you.
Dominique.

Arvind Singh Pundir
Arvind Singh Pundir's picture
Dominiquest wrote:

Dominiquest wrote:

Can anyone please tell me the exact process taking place in the development of Parkinson's disease? I heard from sources that the dopamine producing cells are connected only to the region in the fore brain where they transfer dopamine in order to signal movement and stopping of movement.... My question is, do the dopamine producing cells have connections to any other part of the brain or the body, and if so, where exactly?   I would much appreciate a detailed explaination...
Thank you.
Dominique.

 its an motor system disorder Named after English physician Dr James Parkinson, who first described  disease as “shaking palsy” in 1817 , a small area in the midbrain called the substantia nigra has dopaminergic cells these dopamine-producing cells(neurotransmitter) primarily form connections in the front of the brain, in the corpus striatum, or caudate and putamen it  allows the nervous system to communicate with the muscles in our body. Messages pass between the cells in the substantia nigra and the cells in another part of the brain called the striatum with the aid of dopamine, which acts as a transmitter, in parkinsons the cells of the substantia nigra begins to die so there is less production of dopamine and less transport to the striatum hence there is a imbalance therefore affecting the process like movement,balance,coordination  etc  so the dopamine deficiency in the striatum is responsible for the primary symptoms of the parkinsons disease

Fraser Moss
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specifically it is the

specifically it is the substantia nigra pars compacta (SNpc) that degenerates in Parkinson's Disease.

here is a site that describes the dopaminergic neurotransmitter system
http://www.cellscience.com/CCA.htm

Arvind Singh Pundir
Arvind Singh Pundir's picture
frasermoss wrote:

frasermoss wrote:

specifically it is the substantia nigra pars compacta (SNpc) that degenerates in Parkinson's Disease.

here is a site that describes the dopaminergic neurotransmitter system
http://www.cellscience.com/CCA.htm

yes that's more specific and correct & that's a really useful site
thanks