Probable cause of Death in animal carcinogenicity modal

1 post / 0 new
Kvachhani
Kvachhani's picture
Probable cause of Death in animal carcinogenicity modal

Can any one suggest the probable cause of death in case of animal cancer model (mostly mice) or in regulatory carcinogenicity study? suppress immunity leading to secondry infection is could be the main cause? or intoxication of the tumer tissue & its secretion? or any other?