Macrophage Marker- Mac-2?

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coltifer's picture
Macrophage Marker- Mac-2?

Has anyone used Mac-2 as a macrophage marker?
At a recent conference I saw a lot of groups using it, but am not sure why they would have usen it over F4/80.

Jason King
Jason King's picture
Many dendritic cells are F4

Many dendritic cells are F4/80 positive. It is also possible that Ab Mac-2 is the human equivilent of the murine Ab F4/80. So maybe not the same epitope but the same cell surface molecule.