Senior Bioinformatician to study the intestinal microbiota

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Amar Annamalai
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Senior Bioinformatician to study the intestinal microbiota

Salary range £29750 to £37525 per annum dependent on experience, with a discretionary range to £38980. Closing Date: 16th June 2013

We are looking for a creative and motivated individual to join our dynamic, multi-disciplinary research team investigating the host-pathogen interactions of Clostridium difficile.
Clostridium difficile has rapidly emerged in the past decade as a serious healthcare pathogen and the leading cause of antibiotic-associated diarrhoea. C. difficile disease is linked to a pathological imbalance within the intestinal microbiota, which can be restored with faecal transplantation. The goal of the position is to use advanced genomic techniques and analysis in combination with anaerobic culturing of fastidious organisms from faecal samples to identify signatures of C. difficile susceptibility in humans.
The applicant should have a strong background in bioinformatics and microbiology, and have an interest in learning about host-pathogen interactions and the biology of host-associated microbial communities during health and disease.
Key Responsibilities include:

    Manage large-scale whole-genome sequencing datasets and their associated projectsPerform analysis on datasets generated by next generation sequencing platformsIntegrate sequence data with biological experiments/phenotypic dataLiaise with collaborators and coordinate projectsTrain group membersDevelop software and develop new methods to analyse sequence data

Essential Skills

  • A degree in a relevant biological subject (genetics, biochemistry)
  • Outstanding personal initiative and communication skills
  • Strong publication record in peer-reviewed journals
  • A desire to learn, to innovate and to move out of their comfort zone

Ideal Skills

  • Ability to program in either Perl or Python, or in C/C++ or Java
  • Experience working on sequence data; experience working with next generation sequence data and/or large datasets a bonus
  • Ability to communicate with collaborators across a broad range of fields
  • Ability to work under time pressure and to tight deadlines
  • Ability to lead and drive research projects

Other information

This position is fixed-term for 3 years in the first instance.

Deadline: Tuesday, 18 June 2013

For more details